A Bayesian approach for correcting for partial plating in fluctuation experiments.

Abstract excerpt

The fluctuation experiment is the preferred method for estimating microbial mutation rates. A difficult task facing the data analyst is to infer the mean number of mutations from the number of mutant cells that only indirectly reflects the number of mutations. Partial plating, commonly practised in the laboratory, renders this task even more challenging by allowing only a portion of the mutant cells to be...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteria
• Share to Bayes Theorem
• Share to Colony Count, Microbial