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Article

Hsp72 chaperone function is dispensable for protection against stress-induced apoptosis.

Cell stress & chaperones - 1 May 2009

Chow Ari M, Steel Rohan, Anderson Robin L

Abstract excerpt

In addition to its role as a molecular chaperone, heat shock protein 72 (Hsp72) protects cells against a wide range of apoptosis inducing stresses. However, it is unclear if these two roles are functionally related or whether Hsp72 inhibits apoptosis by a mechanism independent of chaperone activity. The N-terminal adenosine triphosphatase domain, substrate-binding domain and the C-terminal EEVD regulatory motif...

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Identifiers

PMID: 18819021
DOI: 10.1007/s12192-008-0079-4
PMCID: PMC2728260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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