Article
Functional specificity among Hsp70 molecular chaperones.
Science (New York, N.Y.) - 17 Jan 1997
James P, Pfund C, Craig E A
Abstract excerpt
Molecular chaperones of the 70-kilodalton heat shock protein (Hsp70) class bind to partially unfolded polypeptide substrates and participate in a wide variety of cellular processes. Differences in peptide-binding specificity among Hsp70s have led to the hypothesis that peptide binding determines specific Hsp70 functions. Protein domains were identified that were required for two separate functions of a yeast...
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