Article
PRNP gene variation in Pakistani cattle and buffaloes.
Gene - 15 Aug 2012
Imran Muhammad, Mahmood Saqib, Babar Masroor E, Hussain Rashid, Yousaf Muhammad Z, Abid Noman B, Lone Khalid P
Abstract excerpt
Bovine spongiform encephalopathy (BSE) is a neurodegenerative prion protein misfolding disorder of cattle. BSE is of two types, classical BSE and atypical BSE which in turn is of two types, H-type BSE and L-type BSE. Both H-type BSE and L-type BSE are primarily sporadic prion disorders. However, one case of H-type BSE has recently been associated with E211K polymorphism in the prion protein gene (PRNP). Two...
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