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Article

Amplification of pvmdr1 associated with multidrug-resistant Plasmodium vivax.

The Journal of infectious diseases - 15 Nov 2008

Suwanarusk R, Chavchich M, Russell B, Jaidee A, Chalfein F, Barends M, Prasetyorini B, Kenangalem E, Piera K A, Lek-Uthai U, Anstey N M, Tjitra E, Nosten F, Cheng Q, Price R N

Abstract excerpt

BACKGROUND: Multidrug-resistant strains of Plasmodium vivax are emerging in Southeast Asia. METHODS: In vitro drug susceptibility and pvmdr1 genotype were determined in P. vivax field isolates from Indonesia and Thailand. RESULTS: Increased pvmdr1 copy number was present in 21% of isolates from Thailand (15/71) and none from Indonesia (0/114; P < .001). Compared with Indonesian isolates, the median IC(50) of Thai...

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Identifiers

PMID: 18808339
DOI: 10.1086/592451
PMCID: PMC4337975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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