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Article

Plasmodium vivax isolates from Cambodia and Thailand show high genetic complexity and distinct patterns of P. vivax multidrug resistance gene 1 (pvmdr1) polymorphisms.

The American journal of tropical medicine and hygiene - 1 Jun 2013

Lin Jessica T, Patel Jaymin C, Kharabora Oksana, Sattabongkot Jetsumon, Muth Sinuon, Ubalee Ratawan, Schuster Anthony L, Rogers William O, Wongsrichanalai Chansuda, Juliano Jonathan J

Abstract excerpt

Plasmodium vivax accounts for an increasing fraction of malaria infections in Thailand and Cambodia. We compared P. vivax genetic complexity and antimalarial resistance patterns in the two countries. Use of a heteroduplex tracking assay targeting the merozoite surface protein 1 gene revealed that vivax infections in both countries are frequently polyclonal (84%), with parasites that are highly diverse (HE = 0.86)...

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Identifiers

PMID: 23509126
DOI: 10.4269/ajtmh.12-0701
PMCID: PMC3752811

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Source receipt: pubmed, retrieved 7 Sept 2026.

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