Article
Identification of the Plasmodium vivax mdr-like gene (pvmdr1) and analysis of single-nucleotide polymorphisms among isolates from different areas of endemicity.
The Journal of infectious diseases - 15 Jan 2005
Brega Sara, Meslin Benoit, de Monbrison Frédérique, Severini Carlo, Gradoni Luigi, Udomsangpetch Rachanee, Sutanto Inge, Peyron François, Picot Stéphane
Abstract excerpt
Because of the lack of methods for continuous in vitro culture of Plasmodium vivax, little is known about drug-resistance mechanisms in this malaria-causing parasite. Therefore, identification of all the genes potentially involved in drug resistance and of molecular markers related to drug resistance would provide a framework for studying the incidence and spread of drug-resistant P. vivax strains. We have...
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