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Article

Mixed allele malaria vaccines: host protection and within-host selection.

Vaccine - 11 Nov 2008

Barclay Victoria C, Chan Brian H K, Anders Robin F, Read Andrew F

Abstract excerpt

Malaria parasites are frequently polymorphic at the antigenic targets of many candidate vaccines, presumably as a consequence of selection pressure from protective immune responses. Conventional wisdom is therefore that vaccines directed against a single variant could select for non-target variants, rendering the vaccine useless. Many people have argued that a solution is to develop vaccines containing the...

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Identifiers

PMID: 18804509
DOI: 10.1016/j.vaccine.2008.09.004
PMCID: PMC2674600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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