Article
In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic response.
Infection and immunity - 1 Dec 2002
Kennedy Michael C, Wang Jin, Zhang Yanling, Miles Aaron P, Chitsaz Farideh, Saul Allan, Long Carole A, Miller Louis H, Stowers Anthony W
Abstract excerpt
Apical membrane antigen 1 (AMA1) is regarded as a leading malaria blood-stage vaccine candidate. While the overall structure of AMA1 is conserved in Plasmodium spp., numerous AMA1 allelic variants of P. falciparum have been described. The effect of AMA1 allelic diversity on the ability of a recom...
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