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Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks.

Genes, chromosomes & cancer - 1 Jan 2009

Bungaro Silvia, Dell'Orto Marta Campo, Zangrando Andrea, Basso Dario, Gorletta Tatiana, Lo Nigro Luca, Leszl Anna, Young Bryan D, Basso Giuseppe, Bicciato Silvio, Biondi Andrea, te Kronnie Gertruy, Cazzaniga Giovanni

Abstract excerpt

Pediatric acute lymphoblastic leukemia (ALL) comprises genetically distinct subtypes. However, 25% of cases still lack defined genetic hallmarks. To identify genomic aberrancies in childhood ALL patients nonclassifiable by conventional methods, we performed a single nucleotide polymorphisms (SNP) array-based genomic analysis of leukemic cells from 29 cases. The vast majority of cases analyzed (19/24, 79%) showed...

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PMID: 18803328
DOI: 10.1002/gcc.20616

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ETV6
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SMAD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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