Genomic imbalance analysis provides new insight into prognostic factors in adult and pediatric T-ALL.

doi:10.1182/blood.2023022154

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Genomic imbalance analysis provides new insight into prognostic factors in adult and pediatric T-ALL.

Blood - 29 Aug 2024

Balducci Estelle, Simonin Mathieu, Duployez Nicolas, Steimlé Thomas, Dourthe Marie-Emilie, Villarese Patrick, Ducassou Stéphane, Arnoux Isabelle, Cayuela Jean-Michel, Balsat Marie, Courtois Lucien, Andrieu Guillaume, Touzart Aurore, Huguet Françoise, Petit Arnaud, Ifrah Norbert, Dombret Hervé, Baruchel André, Macintyre Elizabeth, Preudhomme Claude, Boissel Nicolas, Asnafi Vahid

Abstract excerpt

ABSTRACT: Given the poor outcome of refractory and relapsing T-cell acute lymphoblastic leukemia (T-ALL), identifying prognostic markers is still challenging. Using single nucleotide polymorphism (SNP) array analysis, we provide a comprehensive analysis of genomic imbalances in a cohort of 317 newly diagnosed patients with T-ALL including 135 children and 182 adults with respect to clinical and biological...

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PMID: 38518104
DOI: 10.1182/blood.2023022154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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