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Article

Genome-wide profiling of genetic alterations in acute lymphoblastic leukemia: recent insights and future directions.

Leukemia - 1 Jul 2009

Mullighan C G, Downing J R

Abstract excerpt

Until recently, our understanding of the genetic factors contributing to the pathogenesis of acute lymphoblastic leukemia (ALL) has relied on the detection of gross chromosomal alterations and mutational analysis of individual genes. Although these approaches have identified many important abnormalities, they have been unable to identify the full repertoire of genetic alterations in ALL. The advent of...

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PMID: 19242497
DOI: 10.1038/leu.2009.18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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