Article
Global genomic characterization of acute lymphoblastic leukemia.
Seminars in hematology - 1 Jan 2009
Mullighan Charles G, Downing James R
Abstract excerpt
A key goal in cancer research is to identify the total complement of genetic and epigenetic alterations that contribute to tumorigenesis. We are currently witnessing the rapid evolution and convergence of multiple genome-wide platforms that are making this goal a reality. Leading this effort are studies of the molecular lesions that underlie pediatric acute lymphoblastic leukemia (ALL). The recent application of...
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