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Article

Microdeletions are a general feature of adult and adolescent acute lymphoblastic leukemia: Unexpected similarities with pediatric disease.

Proceedings of the National Academy of Sciences of the United States of America - 6 May 2008

Paulsson Kajsa, Cazier Jean-Baptiste, Macdougall Finlay, Stevens Jane, Stasevich Irina, Vrcelj Nikoletta, Chaplin Tracy, Lillington Debra M, Lister T Andrew, Young Bryan D

Abstract excerpt

We present here a genome-wide map of abnormalities found in diagnostic samples from 45 adults and adolescents with acute lymphoblastic leukemia (ALL). A 500K SNP array analysis uncovered frequent genetic abnormalities, with cryptic deletions constituting half of the detected changes, implying tha...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18458336
DOI: 10.1073/pnas.0800408105
PMCID: PMC2373322

Genes

EBF1
ETV6
IKZF1
PAX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18458336-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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