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Article

[Role of resistin in insulin resistance].

Rinsho byori. The Japanese journal of clinical pathology - 1 Aug 2008

Onuma Hiroshi, Osawa Haruhiko, Makino Hideichi

Abstract excerpt

Insulin resistance is a major cause of type 2 diabetes mellitus (T2DM). To determine the role of human resistin in T2DM, we analyzed single nucleotide polymorphisms (SNP) in the human resistin gene. We found that the G/G genotype of a resistin SNP at -420 in the promoter region was associated with T2DM (546 cases and 564 controls). Meta-analysis of 1,888 cases and 1,648 controls confirmed this association. Sp1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18800626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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[Role of resistin in insulin resistance].PMID 18800626Read ↗

Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population.Semantic proximity Read ↗

The G/G genotype of a resistin single-nucleotide polymorphism at -420 increases type 2 diabetes mellitus susceptibility by inducing promoter activity through specific binding of Sp1/3.Semantic proximity Read ↗

Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.Semantic proximity Read ↗

Resistin 420C/G gene polymorphism on circulating resistin, metabolic risk factors and insulin resistance in adult women.Semantic proximity Read ↗

A at single nucleotide polymorphism-358 is required for G at -420 to confer the highest plasma resistin in the general Japanese population.Semantic proximity Read ↗

Polymorphism in resistin promoter region at -420 determines the serum resistin levels and may be a risk marker of stroke in Japanese type 2 diabetic patients.Semantic proximity Read ↗

Genome-wide association study of plasma resistin levels identified rs1423096 and rs10401670 as possible functional variants in the Japanese population.Semantic proximity Read ↗

Resistin – 420 C/G polymorphism and serum resistin level in Iranian patients with gestational diabetes mellitusSemantic proximity Read ↗

Resistin G-A haplotype at SNP-420/-358 is associated with the latent sarcopenic obesity index in the toon genome study.Semantic proximity Read ↗

Association between resistin gene -420 C/G polymorphism and the risk of type 2 diabetes mellitus: a meta-analysis.Semantic proximity Read ↗

Novel resistin promoter polymorphisms: association with serum resistin level in Japanese obese individuals.Semantic proximity Read ↗

An inverse association between serum resistin levels and n-3 polyunsaturated fatty acids intake was strongest in the SNP-420 G/G genotype in the Japanese cohort: The Toon Genome Study.Semantic proximity Read ↗

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