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Association between resistin gene -420 C/G polymorphism and the risk of type 2 diabetes mellitus: a meta-analysis.

Acta diabetologica - 1 Apr 2013

Wen Ying, Lu Peng, Dai Ling

Abstract excerpt

Epidemiological studies on the association between the single nucleotide polymorphism (SNP) at -420 C/G (rs1862513) in the human resistin gene (RETN) and the risk of type 2 diabetes mellitus (T2DM) are conflicting. In order to derive a more precise estimation of the association, a meta-analysis was conducted. Twelve studies with 5,935 cases and 5,959 controls were enrolled by searching the databases of Medline,...

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Diabetes Mellitus, Type 2
Gene Frequency
Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 21190046
DOI: 10.1007/s00592-010-0247-8

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RETN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Association between resistin gene -420 C/G polymorphism and the risk of type 2 diabetes mellitus: a meta-analysis.PMID 21190046Read ↗

Association between the RETN -420C/G polymorphism and type 2 diabetes mellitus susceptibility: A meta-analysis of 23 studies.Semantic proximity Read ↗

Association between the resistin gene-420 C>G polymorphism and obesity: an updated meta-analysis.Semantic proximity Read ↗

Genetic variants of resistin and its plasma levels: Association with obesity and dyslipidemia related to type 2 diabetes susceptibility.Semantic proximity Read ↗

Association of resistin (rs3745367) and urotensin II (rs228648 and rs2890565) gene polymorphisms with risk of type 2 diabetes mellitus in Indian population.Semantic proximity Read ↗

Significant interaction between RETN -420 G/G genotype and lower BMI on decreased risk of type 2 diabetes mellitus (T2DM) in Japanese--the J-MICC Study.Semantic proximity Read ↗

Association of RETN +299(G>A) polymorphism with type two diabetes mellitus.Semantic proximity Read ↗

Resistin – 420 C/G polymorphism and serum resistin level in Iranian patients with gestational diabetes mellitusSemantic proximity Read ↗

The +299(G>A) Resistin Gene Polymorphism and Susceptibility to Type 2 Diabetes in ThaisSemantic proximity Read ↗

A at single nucleotide polymorphism-358 is required for G at -420 to confer the highest plasma resistin in the general Japanese population.Semantic proximity Read ↗

Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population.Semantic proximity Read ↗

[The rs10401670 variant of the resistin gene is related to circulating resistin levels, insulin resistance, and presence of type-2 diabetes mellitus in obese patients].Semantic proximity Read ↗

A pilot study suggests that the G/G genotype of resistin single nucleotide polymorphism at -420 may be an independent predictor of a reduction in fasting plasma glucose and insulin resistance by pioglitazone in type 2 diabetes.Semantic proximity Read ↗

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