Article
Plasma resistin, associated with single nucleotide polymorphism -420, is correlated with insulin resistance, lower HDL cholesterol, and high-sensitivity C-reactive protein in the Japanese general population.
Diabetes care - 1 Jun 2007
Osawa Haruhiko, Tabara Yasuharu, Kawamoto Ryuichi, Ohashi Jun, Ochi Masaaki, Onuma Hiroshi, Nishida Wataru, Yamada Kazuya, Nakura Jun, Kohara Katsuhiko, Miki Tetsuro, Makino Hideichi
Abstract excerpt
OBJECTIVE: Resistin, secreted from adipocytes, causes insulin resistance in rodents. We previously reported that the G/G genotype of a resistin gene promoter single nucleotide polymorphism (SNP) at -420 increases type 2 diabetes susceptibility by enhancing promoter activity. We report here on the...
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