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Article

Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.

Biochemical and biophysical research communications - 23 Sept 2005

Osawa Haruhiko, Onuma Hiroshi, Ochi Masaaki, Murakami Akiko, Yamauchi Junko, Takasuka Tomomi, Tanabe Fumiko, Shimizu Ikki, Kato Kenichi, Nishida Wataru, Yamada Kazuya, Tabara Yasuharu, Yasukawa Masaki, Fujii Yasuhisa, Ohashi Jun, Miki Tetsuro, Makino Hideichi

Abstract excerpt

Resistin, secreted from adipocytes, causes insulin resistance in rodents. Its roles and main source in humans remain unknown. The G/G genotype of resistin single nucleotide polymorphism, SNP-420, induces type 2 diabetes mellitus (T2DM) by increasing promoter activity. We elucidated factors correlated with serum resistin and effects of SNP-420 on monocyte resistin mRNA. In 198 T2DM and 157 controls, fasting serum...

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Share to Adipocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

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Source

Identifiers

PMID: 16087164
DOI: 10.1016/j.bbrc.2005.07.122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Resistin SNP-420 determines its monocyte mRNA and serum levels inducing type 2 diabetes.PMID 16087164Read ↗

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