Article
Polymorphism in resistin promoter region at -420 determines the serum resistin levels and may be a risk marker of stroke in Japanese type 2 diabetic patients.
Diabetes research and clinical practice - 1 May 2009
Tsukahara Takayoshi, Nakashima Eitaro, Watarai Atsuko, Hamada Yoji, Naruse Keiko, Kamiya Hideki, Nakamura Nobuhisa, Kato Norihiro, Hamajima Nobuyuki, Sekido Yoshitaka, Niwa Toshimitsu, Tomita Makoto, Oiso Yutaka, Nakamura Jiro
Abstract excerpt
Resistin, which appears to be related to insulin resistance, is secreted mainly from macrophages in human and some of its polymorphisms have been reported. Based on recent in vitro studies, resistin may be associated with atherosclerosis by mediating endothelial hyperactivity. We investigated whether resistin polymorphism at -420C>G is associated with serum resistin levels and diabetic macroangiopathy (coronary...
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