Article
Novel resistin promoter polymorphisms: association with serum resistin level in Japanese obese individuals.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 1 Aug 2004
Azuma K, Oguchi S, Matsubara Y, Mamizuka T, Murata M, Kikuchi H, Watanabe K, Katsukawa F, Yamazaki H, Shimada A, Saruta T
Abstract excerpt
OBJECTIVES: Resistin, an adipocyte-secreted cytokine recently discovered in mice, has been proposed as a link between obesity and diabetes. We analyzed resistin gene polymorphisms and examined their association with serum resistin level and obesity phenotypes in humans. SUBJECTS AND METHODS: Sixty young, obese, non-diabetic subjects taking no medication were studied. DNA sequencing and genotyping of identified...
Topics
- Adenine
- Adult
- Asian People
- Cytosine
- Female
- Guanine
- Hormones, Ectopic
- Humans
- Linkage Disequilibrium
- Male
- Obesity