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Article

Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity.

The Journal of general virology - 1 Oct 2008

Arita Minetaro, Wakita Takaji, Shimizu Hiroyuki

Abstract excerpt

Poliovirus (PV) and enterovirus 71 (EV71) cause severe neurological symptoms in their infections of the central nervous system. To identify compounds with anti-PV and anti-EV71 activities that would not allow the emergence of resistant mutants, we performed drug screening by utilizing a pharmacologically active compound library targeting cellular factors with PV and EV71 pseudoviruses that encapsidated...

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Source

Identifiers

PMID: 18796721
DOI: 10.1099/vir.0.2008/002915-0

Genes

GAK
HIPK2
OAS1
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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