Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino Oligomers

11 Jan 2006

Abstract excerpt

The filoviruses Marburg virus and Ebola virus (EBOV) quickly outpace host immune responses and cause hemorrhagic fever, resulting in case fatality rates as high as 90% in humans and nearly 100% in nonhuman primates. The development of an effective therapeutic for EBOV is a daunting public health challenge and is hampered by a paucity of knowledge regarding filovirus pathogenesis. This report describes a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Viral gastroenteritis research and epidemiology
Share to Viral Infections and Outbreaks Research
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16415982
DOI: 10.1371/journal.ppat.0020001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-Specific Countermeasures against Ebola Virus Based on Antisense Phosphorodiamidate Morpholino OligomersPMID 16415982Read ↗

A Single Phosphorodiamidate Morpholino Oligomer Targeting VP24 Protects Rhesus Monkeys against Lethal Ebola Virus InfectionSemantic proximity Read ↗

VP35 Knockdown Inhibits Ebola Virus Amplification and Protects against Lethal Infection in MiceSemantic proximity Read ↗

Discovery and Early Development of AVI-7537 and AVI-7288 for the Treatment of Ebola Virus and Marburg Virus InfectionsSemantic proximity Read ↗

Evaluation of the potential impact of Ebola virus genomic drift on the efficacy of sequence-based candidate therapeutics.Semantic proximity Read ↗

Antisense oligonucleotide: A promising therapeutic option to beat COVID ‐19Semantic proximity Read ↗

Antisense Oligonucleotide-Based Therapy of Viral InfectionsSemantic proximity Read ↗

A Morpholino Oligomer Targeting Highly Conserved Internal Ribosome Entry Site Sequence Is Able To Inhibit Multiple Species of PicornavirusSemantic proximity Read ↗

Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomersSemantic proximity Read ↗

Development of a Pentacistronic Ebola Virus Minigenome and Its Application to Model Mouse-Adapted Ebola VirusSemantic proximity Read ↗

Inhibition of Flavivirus Infections by Antisense Oligomers Specifically Suppressing Viral Translation and RNA ReplicationSemantic proximity Read ↗

Targeting Marek's disease virus by RNA interference delivered from a herpesvirus vaccineSemantic proximity Read ↗

Advances Toward a Norovirus Antiviral: From Classical Inhibitors to Lethal MutagenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.