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Article

Inhibition of enterovirus 71 replication and the viral 3D polymerase by aurintricarboxylic acid

20 Jan 2010

Abstract excerpt

OBJECTIVES: Enterovirus 71 (EV71) causes serious diseases in humans. The aim of this study was to examine the effects of aurintricarboxylic acid (ATA) on EV71 replication and to explore the underlying mechanism. METHODS: To measure the activity of ATA in inhibiting the cytopathic effect (CPE) of EV71, a cell-based neutralization (inhibition of virus-induced CPE) assay was performed. The effect of ATA was further...

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PMID: 20089540
DOI: 10.1093/jac/dkp502

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