Article
In Vitro Assessment of Combinations of Enterovirus Inhibitors against Enterovirus 71.
Antimicrobial agents and chemotherapy - 1 Sept 2016
Wang Yizhuo, Li Guiming, Yuan Shilin, Gao Qianqian, Lan Ke, Altmeyer Ralf, Zou Gang
Abstract excerpt
Enterovirus 71 (EV-A71) is a major causative pathogen of hand, foot, and mouth disease (HFMD) epidemics. No antiviral therapies are currently available for treating EV-A71 infections. Here, we selected five reported enterovirus inhibitors (suramin, itraconazole [ITZ], GW5074, rupintrivir, and favipiravir) with different mechanisms of action to test their abilities to inhibit EV-A71 replication alone and in...
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