Article
Association of common PALB2 polymorphisms with breast cancer risk: a case-control study.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2008
Chen Peizhan, Liang Jie, Wang Zhanwei, Zhou Xiaoyi, Chen Lu, Li Mian, Xie Dong, Hu Zhibin, Shen Hongbing, Wang Hui
Abstract excerpt
PURPOSE: The PALB2 gene has an essential role in BRCA2-mediated DNA double-strand break repair and intra-S phase DNA damage checkpoint control, and its mutations are moderately associated with breast cancer susceptibility. This study was designed to investigate the common variants of PALB2 and their association with breast cancer risk. EXPERIMENTAL DESIGN: Four single nucleotide polymorphisms (SNP; rs249954,...
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