Genetics risk assessment of PALB2 polymorphism (rs249954 and rs152451) with breast cancer susceptibility among the Pashtun population of Khyber Pakhtunkhwa, Pakistan

Abstract excerpt

<title>Abstract</title> <p>The partner and localizer of <italic>BRCA2</italic> (<italic>PALB2</italic>) gene play an important role in DNA damage repair and control of many biological processes. The occurrence of specific genetic variations, known as single nucleotide polymorphisms (SNPs), in the <italic>PALB2</italic> gene has been identified as a factor contributing to an increased susceptibility to breast canc...

Topics

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• Asian People
• BRCA2 Protein
• Breast Neoplasms
• Case-Control Studies
• China
• Fanconi Anemia Complementation Group N Protein
• Nuclear Proteins
• Tumor Suppressor Proteins

Identifiers and source

Literature Corpus work

743aee25-1f0f-597e-b0bd-1c0549320417

DOI

10.21203/rs.3.rs-4160569/v1