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Article

Polymorphisms in the adenomatous polyposis coli (APC) gene and advanced colorectal adenoma risk.

European journal of cancer (Oxford, England : 1990) - 1 Sept 2010

Wong Hui-Lee, Peters Ulrike, Hayes Richard B, Huang Wen-Yi, Schatzkin Arthur, Bresalier Robert S, Velie Ellen M, Brody Lawrence C

Abstract excerpt

While germline mutations in the adenomatous polyposis coli (APC) gene cause the hereditary colon cancer syndrome (familial adenomatous polyposis (FAP)), the role of common germline APC variants in sporadic adenomatous polyposis remains unclear. We studied the association of eight APC single nucleotide polymorphisms (SNPs), possibly associated with functional consequences, and previously identified...

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Source

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Identifiers

PMID: 20510605
DOI: 10.1016/j.ejca.2010.04.020
PMCID: PMC2924917

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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