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Article

Gene set enrichment analysis using linear models and diagnostics.

Bioinformatics (Oxford, England) - 15 Nov 2008

Oron Assaf P, Jiang Zhen, Gentleman Robert

Abstract excerpt

MOTIVATION: Gene-set enrichment analysis (GSEA) can be greatly enhanced by linear model (regression) diagnostic techniques. Diagnostics can be used to identify outlying or influential samples, and also to evaluate model fit and explore model expansion. RESULTS: We demonstrate this methodology on an adult acute lymphoblastic leukemia (ALL) dataset, using GSEA based on chromosome-band mapping of genes. Individual...

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Identifiers

PMID: 18790795
DOI: 10.1093/bioinformatics/btn465
PMCID: PMC2579710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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