Article
Enrichment of atypical hyperdiploidy and IKZF1 deletions detected by SNP-microarray in high-risk Australian AIEOP-BFM B-cell acute lymphoblastic leukaemia cohort.
Cancer genetics - 1 Apr 2020
Berry Nadine K, Scott Rodney J, Sutton Rosemary, Law Tamara, Trahair Toby N, Dalla-Pozza Luce, Ritchie Petra, Barbaric Draga, Enjeti Anoop K
Abstract excerpt
Acute lymphoblastic leukaemia (ALL) is the most common childhood malignancy with the majority of patients being classified as B-cell lineage (B-ALL). The sub-classification of B-ALL is based on genomic architecture. Recent studies have demonstrated the capability of SNP-microarrays to detect genomic changes in B-ALL which cannot be observed by conventional cytogenetic methods. In current clinical trials, B-ALL...
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