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Article

Importance of C-terminal flexible region of 4E-binding protein in binding with eukaryotic initiation factor 4E.

FEBS letters - 15 Oct 2008

Mizuno Atsuo, In Yasuko, Fujita Yuki, Abiko Fumi, Miyagawa Hiroo, Kitamura Kunihiro, Tomoo Koji, Ishida Toshimasa

Abstract excerpt

Although the alpha-helical Y(X)4Lvarphi containing region of eIF4E-binding protein (4EBP) is the major binding region with eukaryotic initiation factor 4E (eIF4E), the roles of its N- and C-terminal regions in the binding are hardly known. To clarify the roles of these flexible regions in the interaction, the binding features of the sequentially N-, C-, or both-terminal-residue-deleted 4EBP2 mutants were...

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PMID: 18789325
DOI: 10.1016/j.febslet.2008.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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Importance of C-terminal flexible region of 4E-binding protein in binding with eukaryotic initiation factor 4E.PMID 18789325Read ↗

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