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Article

Peripheral and central biodistribution of (111)In-labeled anti-beta-amyloid autoantibodies in a transgenic mouse model of Alzheimer's disease.

Neuroscience letters - 16 Jan 2009

Bacher Michael, Depboylu Candan, Du Yansheng, Noelker Carmen, Oertel Wolfgang H, Behr Thomas, Henriksen Gjermund, Behe Martin, Dodel Richard

Abstract excerpt

Active as well as passive immunization against beta-amlyoid (Abeta) has been proposed as a treatment to lower cerebral amyloid burden and stabilize cognitive decline in Alzheimer's disease (AD). To clarify the mechanism of action underlying passive immunization, the in vivo distribution (and sites of degradation) of peripherally administered radiolabeled human and mouse anti-Abeta antibodies were analyzed in a...

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Source

Identifiers

PMID: 18786612
DOI: 10.1016/j.neulet.2008.08.083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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