Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes.

Neuron - 11 Sept 2008

Butt Simon J B, Sousa Vitor H, Fuccillo Marc V, Hjerling-Leffler Jens, Miyoshi Goichi, Kimura Shioko, Fishell Gord

Abstract excerpt

Previous work has demonstrated that the character of mouse cortical interneuron subtypes can be directly related to their embryonic temporal and spatial origins. The relationship between embryonic origin and the character of mature interneurons is likely reflected by the developmental expression of genes that direct cell fate. However, a thorough understanding of the early genetic events that specify subtype...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Transcription Factors
Share to beta-Galactosidase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electroencephalography

Share to Estrogen Antagonists

Share to Interneurons

Share to Seizures

Share to Tamoxifen

Share to Thyroid Nuclear Factor 1

Source

Open in PubMed Open full text

Identifiers

PMID: 18786356
DOI: 10.1016/j.neuron.2008.07.031
PMCID: PMC2562525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes.PMID 18786356Read ↗

NKX2.1 specifies cortical interneuron fate by activating Lhx6.Semantic proximity Read ↗

Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain.Semantic proximity Read ↗

Independent control of neurogenesis and dorsoventral patterning by NKX2-2Semantic proximity Read ↗

ARX mutation-associated interneuron defects provide insights into mechanisms underlying developmental epilepsies.Semantic proximity Read ↗

Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate.Semantic proximity Read ↗

Distinct Gene Expression Programs Function in Progenitor and Mature Islet CellsSemantic proximity Read ↗

Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways.Semantic proximity Read ↗

Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum.Semantic proximity Read ↗

Origin and molecular specification of striatal interneurons.Semantic proximity Read ↗

Prospective separation and transcriptome analyses of cortical projection neurons and interneurons based on lineage tracing by Tbr2 (Eomes)-GFP/Dcx-mRFP reporters.Semantic proximity Read ↗

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling.Semantic proximity Read ↗

Foxg1 suppresses early cortical cell fate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.