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Article

NKX2.1 specifies cortical interneuron fate by activating Lhx6.

Development (Cambridge, England) - 1 Apr 2008

Du Tonggong, Xu Qing, Ocbina Polloneal J, Anderson Stewart A

Abstract excerpt

In the ventral telencephalon, the medial ganglionic eminence (MGE) is a major source of cortical interneurons. Expression of the transcription factor NKX2.1 in the MGE is required for the specification of two major subgroups of cortical interneurons - those that express parvalbumin (PV) or somatostatin (SST) - but direct targets of NKX2.1 remain to be established. We find that electroporation of Nkx2.1 cDNA into...

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Identifiers

PMID: 18339674
DOI: 10.1242/dev.015123

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SST

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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