Article
Genetic and expression analysis of CASP7 gene in a European Caucasian population with rheumatoid arthritis.
The Journal of rheumatology - 1 Oct 2008
Teixeira Vitor Hugo, Jacq Laurent, Lasbleiz Sandra, Hilliquin Pascal, Oliveira Catarina Resende, Cornelis François, Petit-Teixeira Elisabeth
Abstract excerpt
OBJECTIVE: To study the possible role of the caspase 7 (CASP7) gene in susceptibility to rheumatoid arthritis (RA) in a European Caucasian population. METHODS: CASP7 rs2227309 single nucleotide polymorphism (SNP) was genotyped in 197 French RA trio families and in 252 European RA families available for replication using Taqman allelic discrimination assay. Relative quantification of caspase 7 isoforms alpha and...
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