Article
The chromosome 7q region association with rheumatoid arthritis in females in a British population is not replicated in a North American case-control series.
Arthritis and rheumatism - 1 Jan 2009
Korman Benjamin D, Seldin Michael F, Taylor Kimberly E, Le Julie M, Lee Annette T, Plenge Robert M, Amos Christopher I, Criswell Lindsey A, Gregersen Peter K, Kastner Daniel L, Remmers Elaine F
Abstract excerpt
OBJECTIVE: The single-nucleotide polymorphism (SNP) rs11761231 on chromosome 7q has been reported to be sexually dimorphic marker for rheumatoid arthritis (RA) susceptibility in a British population. We sought to replicate this finding and to better characterize susceptibility alleles in the region in a North American population. METHODS: DNA from 2 North American collections of RA patients and controls (1,605...
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