Article
IL1F7 Gene Polymorphism Is not Associated with Rheumatoid Arthritis Susceptibility in the Northern Chinese Han Population: A Case-Control Study.
Chinese medical journal - 20 Jan 2018
Zhang Xiao-Ying, Zuo Yu, Li Chun, Tu Xin, Xu Hu-Ji, Guo Jian-Ping, Li Zhan-Guo, Mu Rong
Abstract excerpt
BACKGROUND: Interleukin (IL)-37, also called IL1F7, is a natural inhibitor of inflammatory and immune responses. It is involved in the pathogenesis of rheumatoid arthritis (RA). This study aimed to investigate the role of IL1F7 gene polymorphism in RA susceptibility in a large cohort of patients. METHODS: Five selected single-nucleotide polymorphisms in IL1F7 genes (rs2723186, rs3811046, rs4241122, rs4364030, and...
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