Article
Caspase 7 influences susceptibility to rheumatoid arthritis.
Rheumatology (Oxford, England) - 1 Aug 2007
García-Lozano J R, Torres B, Fernández O, Orozco G, Alvarez-Márquez A, García A, González-Gay M A, García A, Núñez-Roldán A, Martín J, González-Escribano M F
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the possible role of the caspase 7 (CASP7) in susceptibility to rheumatoid arthritis (RA). METHODS: Genotyping of three single nucleotide polymorphisms (SNPs) of the CASP7 gene: rs11593766 (G/ T), rs2227310 (C/G) and rs2227309 (G/A) was performed in a total of 906 RA patients and 528 matched healthy controls using TaqMan assays. All the subjects were of Spanish...
Read the complete abstract on PubMed