Article
Association analysis of the interleukin 17A gene in Caucasian rheumatoid arthritis patients from Norway and New Zealand.
Rheumatology (Oxford, England) - 1 Apr 2009
Nordang Gry B N, Viken Marte K, Hollis-Moffatt Jade E, Merriman Tony R, Førre Øystein T, Helgetveit Knut, Kvien Tore K, Lie Benedicte A
Abstract excerpt
OBJECTIVE: Elevated levels of IL-17A have been detected in the inflamed synovium of RA patients, and murine arthritis models deficient in IL17A have shown reduced inflammation. Our aim was to investigate IL17A as a candidate gene for RA, and to assess correlations between risk variants and diseas...
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