Article
Positional cloning of the Igl genes controlling rheumatoid factor production and allergic bronchitis in rats.
Proceedings of the National Academy of Sciences of the United States of America - 16 Sept 2008
Rintisch Carola, Ameri Jacqueline, Olofsson Peter, Luthman Holger, Holmdahl Rikard
Abstract excerpt
Rheumatoid factors (RF), autoantibodies that bind the Fc region of IgG, are one of the major diagnostic marker in rheumatoid arthritis (RA) but occur with lower frequency also in other infectious and inflammatory conditions. Through positional cloning of the previously described quantitative trai...
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