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Article

The genetic control of rheumatoid factor production in a rat model of rheumatoid arthritis.

Arthritis and rheumatism - 1 Dec 2003

Wernhoff Patrik, Olofsson Peter, Holmdahl Rikard

Abstract excerpt

OBJECTIVE: To investigate the genetic regulation of rheumatoid factor (RF) in a rat model of rheumatoid arthritis, in order to gain understanding of the enigmatic role of RF in the disease. METHODS: IgM-RF and IgG-RF, as well as total levels of immunoglobulins of different subclasses, were measured in sera from rats with pristane-induced arthritis (PIA). The major gene regions were identified by linkage analysis...

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Source

Identifiers

PMID: 14674011
DOI: 10.1002/art.11342

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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