Article
Quest for arthritis-causative genetic factors in the rat.
Physiological genomics - 3 Oct 2006
Joe Bina
Abstract excerpt
Experimental rat models of arthritis are extensively studied with a view to understand the genetic underpinnings of rheumatoid arthritis (RA). Genome scans using these models have led to the detection of arthritis regulatory quantitative trait loci (QTLs) on all but three chromosomes of the rat. Whereas some of the QTLs are model specific, others overlap between models. Some arthritis susceptibility and/or...
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