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Article

Mapping and functional characterization of rat chromosome 4 regions that regulate arthritis models and phenotypes in congenic strains.

Arthritis and rheumatism - 1 Feb 2003

Bäckdahl Liselotte, Ribbhammar Ulrica, Lorentzen Johnny C

Abstract excerpt

OBJECTIVE: DA rats are highly susceptible to experimental models of rheumatoid arthritis (RA). Linkage analyses in different models have identified several quantitative trait loci (QTLs) within a 70-cM region of DA rat chromosome 4 (C4). We produced congenic strains for these QTLs in order to map and characterize their impact on arthritis development. METHODS: Selective breeding was used to transfer C4 intervals...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12571866
DOI: 10.1002/art.10782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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