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Article

Identification and isolation of dominant susceptibility loci for pristane-induced arthritis.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2003

Olofsson Peter, Holmberg Jens, Pettersson Ulf, Holmdahl Rikard

Abstract excerpt

Rheumatoid arthritis is a chronic inflammatory autoimmune disorder, controlled by multiple genes as well as environmental factors. With animal models, like the pristane-induced arthritis (PIA) in rats, it is possible to reduce the environmental effects and the genetic heterogeneity to identify chromosomal regions harboring genes responsible for the arthritis development. The PIA model has proved to be useful for...

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PMID: 12817024
DOI: 10.4049/jimmunol.171.1.407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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