Amantadine inhibits an early, M2 protein-dependent event in the replication cycle of avian influenza (H7) viruses.

doi:10.1007/BF01310675

Back to search

Article

Amantadine inhibits an early, M2 protein-dependent event in the replication cycle of avian influenza (H7) viruses.

Archives of virology - 1 Jan 1991

Kendal A P, Klenk H D

Abstract excerpt

Analysis of the effects of amantadine during a single cycle of replication of A/FPV/Rostock virus in vitro showed that, as with other influenza A viruses, an M2 protein-dependent step early in infection was inhibited. No effect was observed on later steps in replication under the conditions used.

Topics

Amantadine
Base Sequence
Influenza A virus
Molecular Sequence Data
Mutation
Viral Matrix Proteins
Viral Proteins
Virus Replication

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.