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Article

Characterization of inhibition of M2 ion channel activity by BL-1743, an inhibitor of influenza A virus.

Journal of virology - 1 Jul 1996

Tu Q, Pinto L H, Luo G, Shaughnessy M A, Mullaney D, Kurtz S, Krystal M, Lamb R A

Abstract excerpt

The influenza A virus M2 integral membrane protein has ion channel activity that can be inhibited by the antiviral drug amantadine. Recently, a spirene-containing compound, BL-1743 (2-[3-azaspiro (5,5)undecanol]-2-imidazoline), that inhibits influenza virus growth was identified (S. Kurtz, G. Lao, K. M. Hahnenberger, C. Brooks, O. Gecha, K. Ingalls, K.-I. Numata, and M. Krystal, Antimicrob. Agents Chemother....

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Identifiers

PMID: 8676445
DOI: 10.1128/JVI.70.7.4246-4252.1996
PMCID: PMC190355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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