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Article

[The mechanisms of the antiviral action of the bora-adamantane derivative preparation BG-12].

Voprosy virusologii - 1 Jan 2000

Markushin S G, Sinitsyn B V, Ginzburg V P, Khaĭder A M, Klimov A I

Abstract excerpt

The effect of one of the derivatives of boraadamantane, preparation BG-12, on reproduction of influenza type A and B viruses was studied. This preparation was shown to inhibit multiplication of a wide range of influenza type A and B virus strains. It is important that BG-12 inhibits in cell culture the replication of a mutant of fowl plague virus A/FPV/Weibridge resistant to remantadine. BG-12 was found to exert...

Topics

Adamantane
Antiviral Agents
Base Sequence
Depression, Chemical
Dose-Response Relationship, Drug
Drug Resistance, Microbial
Electrophoresis, Polyacrylamide Gel
Genome, Viral
Influenza A virus
Influenza B virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Reassortant Viruses

Viral Proteins

Virus Replication

Source

Identifiers

PMID: 8073750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8073750-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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