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Article

Evidence that the MAPK-docking site in MAPKK Dpbs2p is essential for its function.

Biochemical and biophysical research communications - 28 Jul 2006

Sharma Pratima, Mondal Alok K

Abstract excerpt

In eukaryotes, mitogen-activated protein kinase (MAPK) pathways are very important signal transduction modules that regulate various cellular processes. Although eukaryotic cells possess a number of MAP kinase pathways, normally the MAPKKs selectively activate their cognate MAPK. Recent studies suggest that the MAPK-docking site in MAPKK facilitates this specific recognition and activation. However, the role of...

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PMID: 16765917
DOI: 10.1016/j.bbrc.2006.05.155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence that the MAPK-docking site in MAPKK Dpbs2p is essential for its function.PMID 16765917Read ↗

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Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK.Semantic proximity Read ↗

A single MAPKKK regulates the Hog1 MAPK pathway in the pathogenic fungus Candida albicans.Semantic proximity Read ↗

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Identifying protein kinase-specific effectors of the osmostress response in yeast.Semantic proximity Read ↗

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Analyses of the effects of Rck2p mutants on Pbs2pDD-induced toxicity in Saccharomyces cerevisiae identify a MAP kinase docking motif, and unexpected functional inactivation due to acidic substitution of T379.Semantic proximity Read ↗

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