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Article

Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice

28 Nov 2020

Abstract excerpt

BACKGROUND: Obesity and the metabolic syndrome are increasingly prevalent in society and their complications and response to treatment exhibit sexual dimorphism. Mouse models of high fat diet-induced obesity are commonly used for both mechanistic and therapeutic studies of metabolic disease and diabetes. However, the inclusion of female mammals in obesity research has not been a common practice, and has resulted...

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PMID: 33308894
DOI: 10.1016/j.jdiacomp.2020.107795

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