Article
Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells
1 Sept 2008
Abstract excerpt
Microtubule nucleation and formation from the kinetochore/chromatin have been proposed to contribute to bipolar spindle assembly facilitating equal segregation of chromosomes in mitosis. Although two independent pathways involving the small Ran GTPase-TPX2 proteins and the chromosomal passenger complex proteins have been implicated in the formation of microtubules from the kinetochore/chromatin, detailed...
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