Article
SNP genotyping using multiplex single base primer extension assays.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Podini Daniele, Vallone Peter M
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are the most common form of polymorphisms present in the human genome. The single base primer extension (SBE) method is an effective and sensitive tool that can type over 30 known loci scattered throughout an organism's genome in a single reaction. It allows the typing of tetra-allelic SNPs and has been adapted to a broad range of analytical necessities: single-cell...
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